First evidence (from Scythia, modern day Crimea) of a four-wheeled book cart. Within two generations this design was adopted throughout Europe and Asia, replacing the more maneuverable, but much less stable two-wheeled book cart.
The National Library of Babylon, finally switching to papyrus, ceases maintaining its clay tablet shelflist, but is unable to discard it for nostalgic reasons. Two years later, under seige by the Persians, the city finds a new use for the old tablets and manages to inflict severe losses on the beseiging army by pelting them from the ramparts with large quantities of shelflist tablets.
First attested use of an ISBN (for the special collector's edition of Caesar's Gallic Wars with an introduction by Marc Anthony): IXIVVIIXVIIIVIIIVIVII.
The Library at Alexandria decides to contract out its annual weeding project; Vandal hordes are the lowest bidder.
Click the link above and read more librarian geekiness, including an account of "St. Minutia, patron saint of catalogers."